Amobarbital sodium or its brand name Amytal is a barbiturate used for sedative and anti-anxiety effects. This drug was first developed in Germany during the early 20th century. During the first decades of the 1900s, Amytal was used by many to help with insomnia. This was before the discovery and propagation of benzodiazepines as the leading sleep aid in the market.

Amytal is highly addictive and is often abused and usually begins to build up dependency in the body. Amytal works by interacting with the central nervous system while functioning as an agonist for key brain receptors. This, in turn, produces a sedative which relaxes the user and creates an anxiety-free effect.

Experts know of its highly addictive properties when prescribed, and, therefore, Amytal is never recommended to be used long-term. In fact, addiction presents itself after use has exceeded a long time.

What are the Amytal Withdrawal Symptoms?

Barbiturates in nature are prone to become a habit for users. It’s not hard to become tolerant and acquire both physical and psychological dependence. Most of the damage occurs when patients find themselves elevating the dosage in relation to their tolerance levels.

Most people in active barbiturate addiction take a daily dose of 1.5 g, which is exceedingly high. Maintaining the intoxicated levels will increase, leading to the risk of a fatal dosage at some point, something that is not uncommon.

Barbiturate withdrawal symptoms are severe with high levels of mortality. This occurs after the level of therapeutic doses exceed in the body.

Common symptoms of Amytal withdrawal are:

  • Anxiety
  • Muscle spasms, twitching
  • Dizziness
  • Blurred vision
  • Nausea
  • Weakness and tiredness
  • Hypertension

Examples of extreme symptoms:

  • Convulsion
  • Delirium

What are the Stages in the Amytal Withdrawal Timeline?

Sad young woman covering her face

The stages of Amytal withdrawal can vary from person to person.  A 400 mg daily dosage for three months will have a certain amount of physical dependence. However, 700 mg or more, in the span of just a month, can result in severe withdrawal seizures and other symptoms.

Every mind and body is different and will result in different symptoms during the withdrawal juncture. People who have a mental illness will exhibit unique withdrawal manifestations than say, a person who is completely healthy. These factors will always level the symptoms or negatively affect it.

Mixing the drug with any other sedatives or illegal substances can alter the withdrawal experience as well. These things are not uncommon as people are trying to stabilize certain side effects with other drugs. However, the alternative drugs become a secondary problem. This ultimately causes a set of new toxins in which the body has to contend.

There is a timeline that can illustrate the withdrawal stages with Amytal. This timeline is focused on recurring manifestations many users have encountered.

8 To 12 Hours

At this time, withdrawal symptoms are minor but very present. During this stage, you may experience symptoms such as weakness, insomnia, nausea, and muscle spasms. It is the first time the body has been off the drug since it was first used.

During this period, the brain will start to signal the body for more intake of Amytal.


Things at this stage can become a bit more harsh for the patient as withdrawal symptoms increase, and initial symptoms are more present in the body.


Convulsions and delirium are present during the first week.

Many users will find the need to combat these intense feelings with other substances or will return to Amytal use.


At this stage, we begin to see a decline in the intensity of symptoms. In most cases, people will still feel the effects of withdrawal but in a more tolerable manner.

However, rarely do people ever reach this stage without falling into relapse during the first hours or week of quitting cold turkey.


Strong withdrawal symptoms are signs of high intoxication. The best way to rid the body of this is by taking the proper steps to a healthy life. In many instances, people never find the solution to ridding their bodies of the chemicals because they don’t detox. Detox is the best way to be sure your body eliminates existing chemicals that cause addiction.

Why Should I Detox?

Detox is usually supervised by a team of doctors and health experts that administer and monitor a certain amount of medicine or drugs that target withdrawal symptoms. Many times, treatment requires targeting both the physical and psychological effects in the brain.

Seeking recovery, without first entering a detox treatment, is like wishing the addiction would go away. It’s a step that can’t be avoided because it’ll just lead to constant relapse and a harsh withdrawal phase.

Medical intervention during this period of time is meant to ease the withdrawal symptoms that are undeniably going to occur. Since barbiturates have such a strong effect in the body, there is more need to detox. Long-term effects of chronic Amytal abuse will make it harder to quit. And of course, quitting comes with the withdrawal phase that can’t be escaped.

What is the Next Treatment Step?

After detoxing has been completed or is in the process, there are other treatments that are issued or recommended to patients. Each of these treatments is aimed to ensure the patient finds help from their addictions.

The two most common treatments and programs out there, after the detoxification process, are the residential program and the outpatient program. The residential program is a treatment that is applied to each patient in a residential environment. This can last anywhere from less than 30 days to 90+ days. During this period, patients will have access to medical staff and supervision.

For less serious cases of addiction, outpatient programs will do the trick. These programs do not require the patient to live in the facility’s residences, but rather check in regularly. The medical treatment is still highly effective and administered with accuracy. The services are flexible and each case is suited to the client’s needs.

There are other programs such as the relapse prevention program which works with the patient on a plan that’ll help keep them on a path of prevention. Addiction therapy deals with the patients’ motives as to why they were spiraling into addiction in the first place.

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